Sorry, my question wasn't very clear. I meant to ask what sort of biological effect you're hoping to measure using MD.
________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu [freesurfer-bounces@nmr.mgh.harvard.edu] on behalf of Shane Schofield [shane.schofield@yahoo.com] Sent: Friday, August 11, 2017 6:42 AM To: Freesurfer support list Subject: Re: [Freesurfer] Mean diffusivity on cortex?
Hi Dr Yendiki, I am studying a group of people with APOE4 and I want to see whether cortical MD increases can be detected relative to non-carriers, and if so, is the effect size bigger than changes in cortical thickness.
On Friday, August 11, 2017, 11:19:32 AM GMT+1, Yendiki, Anastasia AYENDIKI@mgh.harvard.edu wrote:
What effect are you trying to measure with MD on the cortex?
________________________________ From: Shane Schofield [shane.schofield@yahoo.com] Sent: Friday, August 11, 2017 3:12 AM To: Freesurfer Support List; Yendiki, Anastasia Subject: Re: Mean diffusivity on cortex?
Thanks Dr Yendiki.
I am more interested to compare MD in grey matter regions by putting the MD on the surface, and then do a glmfit type of comparisons. Is that OK? Would you recommend me to smooth the data after spatial normalisation? I have also used the mri_cvs_register as described on the tutorial.
On Friday, August 11, 2017, 7:03:49 AM GMT+1, Shane Schofield shane.schofield@yahoo.com wrote:
Hi DTI Experts,
Is it sensible to do comparisons of MD on the cortex surface like a normal cortical thickness comparisons between group? If the answer is yes, are there recommended on smoothing ?
DT_RECON has been completed in Freesurfer.
Thank you.
_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edumailto:Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.