Re: [Freesurfer] Difference in volumes btw 5.1 and 5,3

Dear Prof. Fischl

Thanks for the valuable comments.

Kim

2014-03-23 3:26 GMT+09:00 Bruce Fischl fischl@nmr.mgh.harvard.edu:

Hi Kim

we of course always strive to make things more accurate, but in the end it will depend on the details of your acquisition and such. I don't think I have a better answer than that, other than to say look at the segmentations and see if you think they are more accurate in one case than the other.

sorry Bruce On Sun, 23 Mar 2014, jh kim wrote:

...

Dear Prof. Fischl Thanks for the prompt response.

The more specific reason of my query is that there was a difference in statistical significance between two FS versions. For example, the result of group comparison of left thalamic volumes

(ANCOVA

...

controlling for age and eICV) is statistically significant (p = 0.04)

when

...

using FS 5.1, whereas the result is no longer significant at all (p =

0.28)

...

in case of FS 5.3. I'm a little confused about this discrepancy. Which result should I trust?

Thank you in advance for your comments.

Kim

2014-03-23 2:59 GMT+09:00 Bruce Fischl fischl@nmr.mgh.harvard.edu: Hi Kim

  there are probably lots of little reasons for the differences.
  This is
  always true for different versions, and the reason we never mix
  versions

  cheers
  Bruce
  On
  Sun, 23 Mar 2014, jh kim wrote:

  > Dear FS lists
  > When I measured subcortical GM volumes in the same subjects by
  using both
  > version 5.1 and 5.3, I have observed a considerable difference
  in volumes
  > between the two versions.
  > For instance, please see the left thalamic volumes below.
  > I cannot figure out why there is much difference between the
  versions.
  > Which result is more reliable?
  >
  > Left-Thalamus-Proper_5.3
  > Left-Thalamus-Proper_5.1
  > 10313
  > 9757
  > 8924.8
  > 7746
  > 9834.8
  > 8287
  > 7935.2
  > 7034
  > 8764.1
  > 7747
  > 9411.8
  > 8037
  > 7636.7
  > 8051
  > 9334.7
  > 8255
  > 10024.3
  > 8171
  > 8757.7
  > 6900
  > 9540.9
  > 8316
  > 9294.4
  > 8369
  > 8091
  > 7366
  > 9103.7
  > 7818
  > 9310.2
  > 7974
  > 7583
  > 6872
  > 9838.9
  > 8911
  > 8829.6
  > 8004
  > 9094.8
  > 6973
  > 9492.3
  > 8922
  > 8821.6
  > 7691
  > 7971.6
  > 7376
  > 9901.2
  > 8936
  > 9773.9
  > 8855
  > 9283.7
  > 7615
  > 8801.6
  > 7690
  > 8505.1
  > 7325
  > 8981
  > 7258
  > 9644.7
  > 8860
  > 9104.2
  > 8298
  > 8494.8
  > 7402
  > 9024.9
  > 7721
  > 8117.8
  > 7226
  > 8001.8
  > 7548
  > 8392.3
  > 7668
  > 8606.6
  > 8173
  > 9126.7
  > 7595
  > 8093
  > 7885
  > 8317.7
  > 7157
  > 10556
  > 9307
  > 8669.6
  > 8374
  > 8034.7
  > 7338
  > 8148.5
  > 7276
  > 9048.1
  > 8064
  > 8160.1
  > 7014
  > 8747.9
  > 7894
  > 8329.9
  > 6866
  > 8415.8
  > 8189
  > 9246.9
  > 8256
  > 8194.1
  > 7183
  > 9629.2
  > 9579
  > 7688.2
  > 6398
  > 8349.2
  > 8238
  > 8366.2
  > 7348
  > 8436.5
  > 7616
  > 8372.3
  > 6977
  > 9396.4
  > 7589
  > 9327.5
  > 7684
  > 10001.8
  > 8627
  > 9762.4
  > 9228
  > 8841
  > 8532
  > 8342.4
  > 8024
  > 8645.7
  > 7725
  >
  > Any comment would be appreciated.
  > Thank you.
  >
  > Kim
  >
  >

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