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In group analysis, is it better to have matched controls (1:1) or to use age, education and other characteristics as confounds in the glm? In the latter situation, we would control for these demographic variables in the glm and the control group n could be smaller, the same or larger than the test group. We are looking at TBI+ and TBI- subjects across a broad age range to look at patterns of cortical thinning. Thanks.
John R. Absher, MD, FAAN GHS Neurosciences jabsher@ghs.orgmailto:jabsher@ghs.org 864-350-6655 (mobile)