Hi, I want to know the what the thickness map represents. As Bruce said in 'measuring the thickness of human cerebral cortex from magnetic resonance images', page 1, paragraph 6, 'The distance between these two surfaces then gives the thickness of the cortical gray matter at any point.'
What physical variable are measured in thickness map? Is it the distance between a vertex in gray/white surface and the corresponding vertex in pial surface.
Whether each vertex in gray/white surface has a match point in pial surface, and vice verse? If true, this means there is a 1-1 mapping between those two surfaces.
If thickness map represents gray matter. How can we get the average thickness of a ROI. Can we draw a ROI in pial surface, then overlay the thickness map to pial surface, and compute the average.
Thanks, Ron
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