25 Apr
2008
25 Apr
'08
12:27 p.m.
Hello,
I was curious if anyone had specific recommendations for correcting ROIs for total brain volume/ICV. From what I can tell, some groups correct each ROI by computing a ratio of ROI/total_brain_volume. Other groups, however, enter total brain volume as a covariate in their statistical models. Both methods seem reasonable, but it seems entering total brain size as a covariate may be more robust, controlling for potential interactions with other IVs (e.g. age, gender). Are there other strategies I am missing?
Any advice is much appreciated!
Thanks!
-Ryan