sorry, I don't remember this case. please repost with our previous correspondence included
On 12/12/16 5:40 PM, Dowling, Kevin Francis wrote:
Hi Doug,
Thank you for your note and my apologies for a delayed response. To create the sig.mgh file we used a volume specific mri_glmfit analysis, omitting the --surf flag and using our volume specific input (ces.nii.gz in SIRP_LoadRegression_Stable5.3_012616_sm5_mni305). I don't know if this information is helpful but when we've run a nearly identical analysis using almost all of the same participants and a different blood folate marker (serum folate) the volumes came out completely fine. I've tried de-meaning the RBC folate values and re-running the mri_glmfit, but the odd activation persists.
This is our mri_glmfit command: mri_glmfit --y /cluster/roffman/users/Stable5_PerRun/Analyses_GDD/GDD_Adults/137_GDD_RBC_Folate_Cond2vfix_KD/SIRP_LoadRegression_Stable5.3_012616_sm5_mni305/Cond2vFix/ces.nii.gz
--fsgd /cluster/roffman/users/fsgd/GDD/137_GDD_Cond2vFix_Covary_RBC_Folate_linear_KDcorrect.fsgd
--C /cluster/roffman/users/fsgd/TwoGroups1CovariateRegressOut1Covariate_KD --glmdir /cluster/roffman/users/Stable5_PerRun/Analyses_GDD/GDD_Adults/137_GDD_RBC_Folate_Cond2vfix_KD/SIRP_LoadRegression_Stable5.3_012616_sm5_mni305/Cond2vFix/2vFix_ClassUsed_Covary_RBCFOLATE_Nuis_Age_Gender
--fwhm 6 --no-prune
Thank you very much, I am most appreciative of your help!
Kind regards, Kevin
*Kevin F. Dowling * Clinical Research Coordinator Brain Genomics Laboratory Division of Psychiatric Neuroimaging Martinos Center for Biomedical Imaging Massachusetts General Hospital 149 13th Street Charlestown, MA, 02129 (p) 617.643.2479
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