It's more a methodological question, and I have asked this before, but I think it could be better discussed in the FreeSurfer community.
Several times people ask me what's the advantage of Surface based methods like the ones used in FreeSurfer over VBM in estimating volumetric parameters of subcortical structures.
The plain question people ask me is: what`s the advantage of FreeSurfer over SPM in terms of volumetric measures.
I have some answers for this. I have wrote something about in the FAQ of FreeSurfer but I was wondering if there's some comparative study or some better idea on this.
----------------------------------------------------------- Pedro Paulo de M. Oliveira Junior Diretor de Operações Netfilter & SpeedComm Telecom --- Novo Netfilter 3.0 www.Netfilter.com.br --- Em breve Netfilter Small Business