Hi all,
First of all, Freesurfer V6 is working like a dream, my 0.7 mm segmentations are running really well and in comparisons to hi-resrecon in 5.3 and early beta, I'm having to do fewer manual corrections!
Now for my questions,
1. I'm running mri_mcsim in order to correct for multiple comparisons via the FS-FAST stream. I'm wondering how many iterations are advised, and how can one check for convergence in an automatic fashion.
I've run the simulations with 1000 and 10,000 iterations on a 1mm segmentation with the FWHM simulations at 8mm. (i.e. using mri_mcsim --o . --base mc-z --save-iter --surf subject lh/rh --nreps 10000 --fwhm 8) and I can't see many differences between the two when correcting for multiple comparisons (i.e. using cluster-sess -analysis myanalysis -thresh 3 -cwp .05 -s SESSION -sign pos).
2. I'm trying to find some references that detail the simulations and form the corrections, does anyone have advice which list I can read/start off with, as well as some key papers that use it (esp on a single subject level). I really like this approach and It does look to circumvent (I think...) a lot of the problems of cluster-wise corrections described with Eklund et al. (Cluster failure paper).
Cheers,
*Dr Kevin Aquino* Research fellow, Sir Peter Mansfield Magnetic Resonance Center, The University of Nottingham.
Honorary Research Fellow School of Physics, Faculty of Science, University of Sydney
*E* Kevin.aquino@nottingham.ac.uk, aquino@physics.usyd.edu.au | *W* https://kevinaquino.github.io http://www.physics.usyd.edu.au/~aquino/
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