External Email - Use Caution
I meant the latter. Thank you very much for responding to my questions.
I have one more question: Can we do non-parametric approaches by Freesurfer?
On Sat, Mar 14, 2020 at 2:13 AM Douglas N. Greve dgreve@mgh.harvard.edu wrote:
Are you asking how to do subcortical analysis or are you asking how to account for subcortical analysis during correction for multiple corrections? For the latter, use --3spaces
On 3/12/2020 2:03 PM, Hengameh Marzbani wrote:
External Email - Use Cautionthank you for your detailed and helpful explanation.
question 3: I mean just left and right. But what should I do if I want to consider subcortical as well as left and right?
Best Regards Hengameh
On Thu, Mar 12, 2020 at 12:07 AM Douglas N. Greve dgreve@mgh.harvard.edu wrote:
On 3/11/2020 4:21 PM, Hengameh Marzbani wrote:
External Email - Use CautionThank you for the quick response.
question 1: I need the results of mri-glmfit (before doing mri-glmfit-sim). I can see the clusters by tksurfer. But, Can I have a text file included all clusters?
You can, the easiest way is to run mri_glmfit-sim and it will give you a list of clusters in a text file. If you set the cwp to 1, then it will give you all the clusters. See the help.
question 3: I want to do the analyse by considering the whole brain. Is correct to use --2spaces? and also I I want to visualize the results in both hemisphere simultaneously. is it possible by freeview?
Whole brain meaning left, right, and subcort or just left and right? If just left and right, then use --2spaces
question 5: I can't understand what is the reason of using demean and normalize. Would you mind explaining to me? And when is it necessary to use them?
Demeaning makes the design matrix better conditioned. But also if you are looking at the difference in average thickness between two groups regressing out, eg, age, then simply using age as a regressor will reduce the efficiency of the estimation because the age itself will have a non-zero mean, so the regression is left trying to figure out what part of the thickness average is due to the group and what part is due to age.
Thank you so much.
Hengameh
On Tue, Mar 10, 2020 at 2:03 AM Douglas N. Greve dgreve@mgh.harvard.edu wrote:
On 3/9/20 5:53 PM, Hengameh Marzbani wrote:
External Email - Use CautionHello Freesurfer developers, 1- I want to extract the uncorrected clusters from the uncorrected
significance maps obtained from mri_glmfit for structural data (to illustrate cluster, size, location, and significance) like abs.sig.cluster.summary (summary of clusters (text))which is obtained from mri_glmfit-sim. Is there a way to do this? Set the clusterwise p-value thresh to 1 (--cwp 1)
2- I don't see any clusters when I use cluster-based correction for
multiple comparisons (for example mri_glmfit-sim \ --glmdir lh.Area.glmdir \ --sim mc-z 10000 2 mc-z.abs\ --sim-sign abs --cache 4 neg \ --cwp 0.05\ --2spaces). How much is it significant if I report the uncorrected clusters? Usually, reveiewers won't let you report exclusivly uncorrected results.
3- Are there new ways of looking at the whole brain together (not left
and right hemisphere separately)by Qdec and FSGD? You can load both hemispheres into freeview, if that is what you mean
4- How can I do fdr correction in mri_glmfit-sim? what flag should I
use? You can't, use mri_fdr. Run with --help to get docs
5- How can I demean and normalize the covariates when I use FSGD? what
flag should I use? Add these lines in your FSGD file DeMeanFlag 1 ReScaleFlag 1
Thanks you in advance! Best regards, Hengameh
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