Hi Panos,
It all depends on what your question is: whether the between-group difference in LGI and surface area is an absolute difference (then don't correct), or whether you want to see if it holds after correction. In any case, by geometric definition, the relationship between surface area, and thus LGI, and volume is governed by a power law, which means that if you linearly correct for intracranial volume, some of its effect will remain.
Hope it helps,
Marie
On Jul 10, 2014, at 10:57 AM, pfotiad@nmr.mgh.harvard.edu wrote:
Hi FS Community,
I was wondering whether LGI and Surface Area need to be corrected for total Intracranial Volume.
Thanks in advance, Panos _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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