Re: [Freesurfer] ADNI protocol anisotropic resolution

Hi Antonio

yes, that should be fine. It probably reduces sensitivity in some regions, but given the complexity of the folds I would expect it to average out. That said, no one has ever done such a study so we really don't know.

cheers Bruce

On Wed, 19 Nov 2014, Antonio Algaze Beato wrote:

Dear group, I am new to FS and the ADNI protocol, thus my question: is it ok to have a slice thickness of 1.2 mm and in-plane resolution of 1.05 mm for cortical segmentation and brain volume analyses? This seems to be a sequence suggested on the FreeSurferWiki (I am using a GE750 3T).  Doesn't the anisotropic resolution introduce a bias?

Thanks a lot!

-- Antonio Algaze, PhDUniversity of Puerto Rico Physics, UPR-Bayamón Radiology, UPR-School of Medicine