External Email - Use Caution
Hi Bruce,
Thank you very much for your answer.
Kind regards, Rosie
On Sun, Nov 21, 2021 at 8:04 PM Fischl, Bruce BFISCHL@mgh.harvard.edu wrote:
Hi Rosie
It really depends on what your hypotheses are, but if you are covarying for age and gender in thickness you probably want to do so in an analysis of volume as well. The only real difference are (1) thickness doesn’t really need TBV covariation, and (2) thickness is a more localizable quantity than volume. Of course they are different neurobiologically as well, but from an analysis standpoint those are the two big differences
Bruce
*From:* freesurfer-bounces@nmr.mgh.harvard.edu < freesurfer-bounces@nmr.mgh.harvard.edu> *On Behalf Of *Rosalia Dacosta Aguayo *Sent:* Sunday, November 21, 2021 1:42 PM *To:* Freesurfer support list freesurfer@nmr.mgh.harvard.edu *Subject:* [Freesurfer] Basic question
External Email - Use Caution *Dear Freesurfer team,
I know this is a basic question, but I would like to be sure before proceeding. Are those statements below right?
For cortical thickness, I should covariate for age and sex
For volume, I should covariate only for TBV
Thank you for your time and your patience.
Best wishes,
Rosie
Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://secure-web.cisco.com/1UoHl-aIm8K2Jins6WNMukvp1N7s1N3PEqPPEyEozsWoy5o... The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at http://secure-web.cisco.com/13b1Kw0iqhzWIA2zmmelxSnrAB9TwOqzKaamm_tPr9lx1lJC... . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.