This is a standard type of group analysis using a single covariate. You can set up an FSGD file specifying the groups as classes and using allele load as a continuous variable. If you're not interested in the differences between the slopes, then use a DOSS model when you run mri_glmfit. Search for FSGD on the wiki for more info.
doug
Adam Nitenson wrote:
Hi all,
So far I have only been using Freesurfer analyses to look at thefunctional activation for individuals, single groups, and subtractions between 2 groups. We now want to investigate a possible linear relationship between allele load (Three levels: 0,1,2) and functional activation. Is there a way to create a brainmap using glmfit or some other command that displays voxels that display a significant regression of genotype (such as red for positive / blue for negative linear relationship)? Basically, it would be a map that shows significant "r" instead of significant difference.
Thanks,
Adam Nitenson, B.S. Brain Genomics Lab Massachusetts General Hospital _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer