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Dear FreeSurfer experts,
I would like to confirm my FSGD file format and mtx contrasts prior to continuing with my analyses. Here is some background information: I have two groups (treatment, control) and would like to determine whether our quantitative scale, CDRISC, is associated with thickness within each group. I would like to control for sex, handedness, and age. Seeing as sex and handedness are categorical, I entered them as Classes instead of variables (Controlleftmale was not included, as no participant fell in that group).
GroupDescriptorFile 1 Title CDRISC Class Controlrightfemale Class Controlleftfemale Class Treatrightfemale Class Treatleftfemale Class Controlrightmale Class Treatrightmale Class Treatrightmale Variables CDRISC_TREATMENT CDRISC_CONTROL age Input sub-1 Controlrightfemale 0 19 10.66 Input sub-2 Controlleftfemale 0 26 14 Input sub-3 Treatrightmale 35 0 14.02 Input sub-4 Treatleftmale 35 0 10.16 [...]
My contrasts (DOSS) are as follows:
[Nregressors = Nclasses + Nvariables Nregressors = 7 + 3 Nregressors = 10]
Treatment CDRISC slope = 0 0 0 0 0 0 0 1 0 0 Control CDRISC slope = 0 0 0 0 0 0 0 0 1 0
Are there any glaring issues with this model? The only extra step of consideration here is that I have yet to demean the data. Any guidance is appreciated.
Warm regards, Olivier Brown