Re: [Freesurfer] interpreting qdec results

No, I've never used SPSS. If you know matlab, I can step you through how to do it there

On 06/25/2014 04:13 PM, Emma Thompson wrote:

I'm using SPSS. I'm not sure if my analysis reflects exactly what qdec is doing, do you know which analysis in SPSS would be most appropriate? I'm doing a simple ANCOVA.

On Wed, Jun 25, 2014 at 11:07 AM, Douglas N Greve <greve@nmr.mgh.harvard.edu mailto:greve@nmr.mgh.harvard.edu> wrote:

what software did you use? Are you sure you are using the same
model as
qdec uses?


On 06/25/2014 11:03 AM, Emma Thompson wrote:
> Thanks Doug, yes I did control for age in both instances.
>
>
> On Wed, Jun 25, 2014 at 10:14 AM, Douglas N Greve
> <greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
<mailto:greve@nmr.mgh.harvard.edu
<mailto:greve@nmr.mgh.harvard.edu>>> wrote:
>
>
>     Your interpretation is right (ie, controls > patients for
>     red/yellow/orange). When you compared the two groups in your
separate
>     analysis, did you control for age?
>     doug
>
>
>     On 06/24/2014 02:19 PM, Emma Thompson wrote:
>     > Hi Freesurfers,
>     > I am reposting this as my last email bounced.
>     >
>     > I have conducted a DODS analysis in qdec with group
(controls vs
>     > patients) set as my fixed factor and age as a nuisance
variable to
>     > determine if my groups differ in cortical thickness.
Controls were
>     > added first in the .levels file followed by patients. When I
>     view the
>     > results in the display window for "do controls differ from
>     patients in
>     > cortical thickness" I see a significant cluster for the caudal
>     > anterior cingulate, denoted by a red-orange blob and a
positive
>     > t-value. I'm wondering if this simply means that controls had
>     greater
>     > cortical thickness compared to patients after controlling for
>     age? The
>     > reason I ask is that I'm a little confused since when I
created
>     an ROI
>     > for this cluster using tksurfer and then extracted the
means and
>     sd, I
>     > see that the patients actually have larger means than the
controls,
>     > the opposite of my interpretation of the results presented by
>     the qdec
>     > display. Furthermore, if I extract the means and sds for
the entire
>     > caudal anterior cingulate using the aparc file, I get
means that are
>     > larger in controls, compared to patients, which seems
consistent
>     with
>     > qdec. Any ideas? Thanks for all the help.
>     >
>     >
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>     MGH-NMR Center
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--
Douglas N. Greve, Ph.D.
MGH-NMR Center
greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu>
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