Hi Catherine,
it shouldn't be necessary, but you should be very careful that any effects you find are biological ones and don't simply reflect acquisition differences.
cheers Bruce On Wed, 14 Dec 2011, Cat Chong wrote:
Dear Experts,
I am sorry for the basic question but we have a dataset of subjects we like to analyze for which we have different slice thicknesses and orientations in dicom format. All T1's collected were SPGR volumes with the same scanner parameters. My question was: Do you advice to re-orient and re-slice the dataset to make it uniform or is that step not necessary
cheers and thank you catherine