Ciao Luigi, I haven't tried FLAIR for images the subfields, but if you sent me a high-res FLAIR acquisition of the hippocampus, I could take a look. If you are doing T2, you could implement the procotol used in ADNI: coronal slices with 0.4x0.4 in plane resolution, with 2mm slice separation (ideally, you would position the box in an slightly oblique positions such that the coronal slices cut the hippocampus perpendicularly to it major axis). Cheers, Eugenio
Juan Eugenio Iglesias Postdoctoral researcher BCBL www.jeiglesias.com www.bcbl.eu
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From: "Luigi Antelmi" luigi.antelmi@gmail.com To: "Freesurfer support list" freesurfer@nmr.mgh.harvard.edu Sent: Monday, January 25, 2016 9:43:29 AM Subject: [Freesurfer] hippocampal subfields - multispectral segmentation with FLAIR
Dear members,
in our center we are evaluating whether to introduce a T2 into a protocol that, among others, already includes a T1 and a FLAIR sequences.
Our main concern is to to maximize the information-to-duration ratio of the entire protocol.
In order to improve the subfields' segmentation we read that it is better to add a T2 or "other" sequences.
Will the FLAIR alone (+T1) can work well as the T2?
If instead the T2 is preferable, what is the coarsest-but-still-informative resolution you suggest?
Thank you for sharing your experience!
Have a nice day, Luigi.
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