I am forwarding Hengameh's questions to the list since I am not sure about the answers and somehow she couldn't send emails to the list (do people need to subscribe to the list first?).
Please help if you know the answers to her questions.
Thanks, -Xiao
---------------------------------------- From: hengameh haghighat hhaghighat@razi.tums.ac.ir
I have three problems with FreeSurfer software.
1- I don't know how to segment the hippocampus with FreeSurfer software.
For this reason i segmentated the hippocampus with another software (MRIcro) and then gave these slides to FreeSurfer software for measuring volume of hippocampus. The obtained volume was greater than the normal volume. For this reason I made a phantom with the specific volume of 27.142 cm3 to obtained correction factor.
2- In the guide's FreeSurfer it is said when watershed algorithm is corrupted , change the preflooding height to 30% in the setting section of RmSkull tab in expert preference , however I didn't get any result.
3- when an analyze file including one slide or all of the taken slides are given to the FreeSurfer software the watershed algorithm is corrupted and the volume is not calculated .
4- How much is the difference between the volume of the subject brain with FreeSurfer software (Albert) and the obtained volume in FreeSurfer software? how have you obtained it's correction factor?
I would be thankful if you help me in this matter. I look forward to hearing for you soon
Sincerely Yours