If you can get it past the reviewers. It might be better to report the actual significance of the clusters.
doug
liang wang wrote:
Hello Doug,
Thanks for your kind response. I have tried to use mri_glmfit-sim to correct the results. However, no significant differences were observed. To compare with other studies, I would like to report the results (p < 0.001, uncorrected) and mention that they will disappear if corrected by cluster-based threshold method. Is it a acceptable way?
Liang
2010/7/11 Douglas N Greve <greve@nmr.mgh.harvard.edu mailto:greve@nmr.mgh.harvard.edu>
You should correct for multiple comparisons using cluster-wise correction. See the tutorials on group analysis on our wiki. doug liang wang wrote: Hi, Using mri_glmfit, I found significant between-group difference in cortical thickness in some regions. However, there are a lot regions with very small vertices surviving the given threshold. What I need to do is displaying large clusters (e.g. having 20 vertices at least) assumed as "true" difference. I don't know how to make it by a selected threshold of cluster size . Any suggestions would be appreciated. Liang -- Liang Wang, PhD Postdoctoral Fellow Woodward Lab Department of Psychiatry University of British Columbia BC Mental Health & Addiction Services 938 West 28th Avenue Vancouver BC V5Z 4H4 Telephone: 1-604-875-2000 (ext. 4735) Fax: 1-604-875-3871 Email: wanglbit@gmail.com <mailto:wanglbit@gmail.com> <mailto:wanglbit@gmail.com <mailto:wanglbit@gmail.com>> ------------------------------------------------------------------------ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu <mailto:greve@nmr.mgh.harvard.edu> Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting <http://surfer.nmr.mgh.harvard.edu/fswiki/BugReporting> FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>-- Liang Wang, PhD Postdoctoral Fellow Woodward Lab Department of Psychiatry University of British Columbia BC Mental Health & Addiction Services 938 West 28th Avenue Vancouver BC V5Z 4H4 Telephone: 1-604-875-2000 (ext. 4735) Fax: 1-604-875-3871 Email: wanglbit@gmail.com mailto:wanglbit@gmail.com
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