Hi FreeSurfer experts,
When running mri_glmfit I am getting the error "matrix is ill-conditioned or badly scaled, condno=10182.4"
My fsgd file is attached to this email.
My command is:
mri_glmfit --y /cluster/roffman/users/Stable5_PerRun/Analyses_GDD/GDD_Adults/144_GDD_Thickness_RBC_Folate/lh_thickness_map.mgh --fsgd /cluster/roffman/users/fsgd/GDD/144_GDD_CT_Covary_RBC_Folate_linear.fsgd --surf fsaverage lh --fwhm 4.6 --C /cluster/roffman/users/fsgd/OneGroupOneCovariateRegressOut2Covariates.mtx --glmdir /cluster/roffman/users/Stable5_PerRun/Analyses_GDD/GDD_Adults/144_GDD_Thickness_RBC_Folate/LH_CT_Covary_RBC_Folate_Nuis_Gender_Age_linear
The design matrix is:
1.000 2.981 -0.403 -1.054; 1.000 3.033 2.219 -1.054; 1.000 3.051 0.239 0.943; 1.000 3.033 0.150 0.943; 1.000 2.901 -0.586 -1.054; 1.000 3.036 -0.834 -1.054; 1.000 2.945 -0.482 -1.054; 1.000 2.977 1.055 0.943; 1.000 2.936 -0.627 0.943; 1.000 2.990 0.586 -1.054; 1.000 2.943 -0.479 0.943; 1.000 2.912 -0.530 0.943; 1.000 2.879 0.777 -1.054; 1.000 2.958 -0.630 0.943; 1.000 2.929 -0.520 0.943; 1.000 2.962 0.140 0.943; 1.000 3.071 2.194 0.943; 1.000 3.017 0.619 -1.054; 1.000 2.992 -0.314 -1.054; 1.000 3.021 -0.579 0.943; 1.000 3.041 -0.467 0.943; 1.000 2.963 0.930 0.943; 1.000 3.017 0.729 0.943; 1.000 3.027 -0.314 0.943; 1.000 3.097 0.680 -1.054; 1.000 2.985 1.091 0.943; 1.000 3.034 -1.562 -1.054; 1.000 3.039 -0.370 0.943; 1.000 2.954 -0.191 0.943; 1.000 3.045 -0.907 -1.054; 1.000 3.004 -0.492 0.943; 1.000 3.049 -1.468 0.943; 1.000 2.951 1.006 -1.054; 1.000 2.975 0.135 -1.054; 1.000 3.057 0.489 0.943; 1.000 3.017 0.474 -1.054; 1.000 2.976 -0.168 0.943; 1.000 2.989 1.993 0.943; 1.000 3.056 0.859 0.943; 1.000 2.953 -1.124 -1.054; 1.000 3.018 -1.172 -1.054; 1.000 2.928 -0.194 -1.054; 1.000 2.922 -0.546 -1.054; 1.000 2.857 -0.171 -1.054; 1.000 2.968 -0.120 -1.054; 1.000 2.925 1.784 0.943; 1.000 2.992 -0.874 0.943; 1.000 2.798 -1.058 -1.054; 1.000 3.007 -0.268 -1.054; 1.000 2.975 -0.237 0.943; 1.000 2.992 -0.449 -1.054; 1.000 3.123 -0.558 -1.054; 1.000 3.013 -0.181 -1.054; 1.000 2.993 1.096 -1.054; 1.000 2.961 1.605 0.943; 1.000 2.907 -0.749 -1.054; 1.000 2.897 -0.693 -1.054; 1.000 2.964 0.013 -1.054; 1.000 2.927 1.315 -1.054; 1.000 3.022 -0.752 -1.054; 1.000 2.943 -0.637 0.943; 1.000 2.999 -0.467 -1.054; 1.000 3.012 0.535 -1.054; 1.000 2.984 1.766 -1.054; 1.000 2.975 -0.553 -1.054; 1.000 3.030 -0.650 0.943; 1.000 2.902 -1.048 -1.054; 1.000 2.954 -0.502 -1.054; 1.000 3.031 -0.749 -1.054; 1.000 3.051 -0.510 0.943; 1.000 3.033 -0.074 0.943; 1.000 3.090 0.856 0.943; 1.000 2.961 0.894 -1.054; 1.000 3.056 0.239 -1.054; 1.000 2.990 2.484 0.943; 1.000 2.999 -1.218 -1.054; 1.000 3.014 -0.311 0.943; 1.000 3.064 -0.512 0.943; 1.000 2.894 -1.178 -1.054; 1.000 2.944 -1.539 0.943; 1.000 2.926 -1.542 0.943; 1.000 3.051 -0.897 -1.054; 1.000 2.995 -1.532 -1.054; 1.000 2.997 0.048 -1.054; 1.000 2.980 -0.214 0.943; 1.000 3.006 -0.275 -1.054; 1.000 2.930 0.912 -1.054; 1.000 2.857 -1.364 0.943; 1.000 3.023 -0.013 0.943; 1.000 3.048 0.158 0.943; 1.000 2.953 1.292 0.943; 1.000 2.922 1.065 0.943; 1.000 3.009 -1.552 0.943; 1.000 2.946 -0.296 0.943; 1.000 3.031 2.072 -1.054; 1.000 2.910 2.671 0.943; 1.000 2.971 -0.405 -1.054; 1.000 2.976 0.043 -1.054; 1.000 3.007 -0.339 0.943; 1.000 3.030 -0.232 0.943; 1.000 2.972 -0.018 0.943; 1.000 2.924 -0.693 0.943; 1.000 3.003 0.301 -1.054; 1.000 3.034 0.374 -1.054; 1.000 3.070 -0.551 -1.054; 1.000 2.943 2.365 0.943; 1.000 3.035 -0.979 -1.054; 1.000 2.926 -1.575 0.943; 1.000 2.954 -0.390 -1.054; 1.000 2.966 0.777 -1.054; 1.000 2.992 0.102 0.943; 1.000 2.887 -0.005 0.943; 1.000 3.136 -1.330 -1.054; 1.000 2.941 -0.813 0.943; 1.000 2.953 -0.816 -1.054; 1.000 2.914 -0.997 -1.054; 1.000 3.039 2.365 0.943; 1.000 3.009 -0.441 -1.054; 1.000 3.066 -1.127 0.943; 1.000 2.985 -0.441 -1.054; 1.000 2.874 0.910 0.943; 1.000 2.989 0.326 0.943; 1.000 2.985 0.777 -1.054; 1.000 3.021 0.797 0.943; 1.000 3.015 -0.227 0.943; 1.000 2.972 -0.191 0.943; 1.000 3.017 -0.500 0.943; 1.000 2.914 2.553 -1.054; 1.000 3.096 -0.265 -1.054; 1.000 3.073 1.052 -1.054; 1.000 3.020 -0.765 0.943; 1.000 3.146 1.078 0.943; 1.000 2.917 -0.609 0.943; 1.000 2.974 -0.326 0.943; 1.000 2.909 0.889 0.943; 1.000 3.108 -1.236 0.943; 1.000 3.073 -0.224 -1.054; 1.000 3.033 -0.625 0.943; 1.000 2.970 1.949 0.943; 1.000 3.008 2.214 0.943; 1.000 2.981 0.787 0.943; 1.000 3.102 -0.966 -1.054; 1.000 2.930 0.512 0.943; 1.000 2.934 -1.547 0.943;
Do you know what is going on and how I can fix it?
Thank you for your help!
Anais Rodriguez-Thompson Clinical Research Coordinator Brain Genomics Laboratory Martinos Center for Biomedical Imaging Massachusetts General Hospital Phone: (617) 643-3215