in general you are better off making the average of your subjects, and displaying results on it, as it will more accurately reflect the true cross-subject registration. I've attached a script for doing so, make sure to set the SUBJECTS env variable to be the list of subjects you want to average, and it will create an "average" subject. Note that you don't need to rerun any morphing - this will use the current morph to build an average.
cheers, Bruce
On Fri, 27 Aug 2004 L.Scheef@uni-bonn.de wrote:
Dear list members!
I would like to analye cortical thickness data and wonder which is the best way to proceed...
So far I have processed the data using recon all (including manual top fixing). This includes the registration using the average7 subj. on the sphere.
- Is it a valid approach to use the coreg. on the average7 or should
I take a similar approach as used by VBM building a study specific template and do the coreg step on this template once again.
- For doing the cortical thickness group analysis (using mris_glm) it
seems to be the best to use a specific group average. Is there any "ready to use script" which I could use to build the average_study data and all the stuff needed by mris_glm?
- Which files should be calculated to use them later for the stat.
analysis and overlay?
Many thanks for your help!
Best wishes,
Philppe and Lukas
Lukas Scheef, MD, MSc MR-Tomography Department of Radiology University of Bonn Sigmund-Freud-Straße 25 D-53105 Bonn Fax: +49-228-287-5598 Phone:+49-228-287-4496 E-mail: L.Scheef@uni-bonn.de
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