Dear Freesurfer-Experts,
I am currently trying to measure Cortical Thickness of a Volume-defined ROI in a patient measured at 4 timepoints.
Basically, I am interested in a ROI resulting from fMRI activation measured on Timepoint 1. I would then like to get thickness values in the same ROI for all Timepoints 1-4.
I have read the instructions here: https://surfer.nmr.mgh.harvard.edu/fswiki/VolumeRoiCorticalThickness this works.
now, my idea is:
ROI from TP1 >> register to base image of longit. recon. ("base") ROI from base >> TP1.long (from long recon) ROI from base >> TP2.long (from long recon) ROI from base >> TP3 long (from long recon) ROI from base >> TP4.long (from long recon)
OR should I simpy map my ROI to fsaverage and project it back all individual timepoints? ROI from TP1 >> register to fsaverage ROI from fsaverage >> TP1 (not from long recon) ROI from fsaverage >> TP2 (not from long recon) etc.
I understand that registration using the long. recon is more robust...
Best regards, Bastian