Sorry, I didn't note I was replying to you only.. Anyway, thank you for the reply! So I will apply the command I mentioned to you in my previous e-mail to create flipped RH and LH surfaces for the subjects with the right hemisphere affected. Should I register to the fsaverage_sym atlas also the subjects I don't want to flip (i.e., those with the left hemisphere affected), to pool them together in the statistic with the flipped subjects? Thank you again Paola
Paola Valsasina, MSc Research Fellow Neuroimaging Research Unit (Director Prof. M. Filippi) Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute and University "Vita-Salute" San Raffaele Via Olgettina 60, 20132 Milan, Italy
-------------------------------------------------------------------------- IL MIO 5XMILLE VA AL SAN RAFFAELE DI MILANO PERCHE' QUI LA RICERCA DIVENTA CURA. CF 07636600962 SE NON QUI, DOVE? Info: 5xmille@hsr.it - http://www.5xmille.org/
Disclaimer added by CodeTwo Exchange Rules 2007 http://www.codetwo.com -----Messaggio originale----- Da: Douglas N Greve [mailto:greve@nmr.mgh.harvard.edu] Inviato: martedì 22 aprile 2014 17.56 A: Valsasina Paola; Freesurfer@nmr.mgh.harvard.edu Oggetto: Re: R: [Freesurfer] Filipping issue
Hi Paola, please remember to post to the list and not to us personally. thanks! I would still use the xhemi tools for this. If you have N subjects, you will get 2*N surfaces aligned to the fsaverage_sym atlas. You can then just pick the ones you want to analyze further doug
On 04/22/2014 08:34 AM, Paola Valsasina wrote:
Dear Doug,
We have followed your suggestion and we performed the recon-all analysis
for
all study subjects (till autorecon3) on non-flipped images.
I am now reading the instructions on the wiki about the xhemi tool, but I
am
not 100% sure they apply to our case.
The wiki instructions describe a comparison between LH and RH within subjects (i.e., an analysis of cortical asymmetry), whereas we would like simply to L-R flip the final surfaces of patients having a RH damage, so that all patients have the damage in the LH. Then, we would like to compare them with control subjects.
For this purpose, is it sufficient to register the patients lesioned in
the
RH to the symmetric template with the --xhemi option?
(i.e. surfreg --s subject_name --t fsaverage_sym --xhemi --rh --lh)
Then, how do we perform final statistical analysis?
Thank you in advance for any suggestion! Kind regards Paola
Paola Valsasina, MSc Research Fellow Neuroimaging Research Unit (Director Prof. M. Filippi) Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute and University "Vita-Salute" San Raffaele Via Olgettina 60, 20132 Milan, Italy
IL MIO 5XMILLE VA AL SAN RAFFAELE DI MILANO PERCHE' QUI LA RICERCA DIVENTA CURA. CF 07636600962 SE NON QUI, DOVE? Info: 5xmille@hsr.it - http://www.5xmille.org/
Disclaimer added by CodeTwo Exchange Rules 2007 http://www.codetwo.com
-----Messaggio originale----- Da: freesurfer-bounces@nmr.mgh.harvard.edu [mailto:freesurfer-bounces@nmr.mgh.harvard.edu] Per conto di Douglas N
Greve
Inviato: giovedì 13 febbraio 2014 21.50 A: freesurfer@nmr.mgh.harvard.edu Oggetto: Re: [Freesurfer] Filipping issue
Definitely #2. You should use the xhemi tools http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi First run them through recon-all as normal, then follow the steps on the wiki. Contact the list again to get instructions for the final analysis.
doug
On 02/13/2014 08:23 AM, Paola Valsasina wrote:
Dear List,
we are starting the analysis of cortical thickness for a group of patients who have only one side affected. The majority of patients have the left hemisphere affected, but some patients have the right hemisphere affected. In order to do a group analysis, we would like to flip the images of some patients, so that the affected side is left for all subjects.
Which is the best way to do this:
1)flip the 001.mgz volume and perform the entire recon-all pipeline with flipped images;
or
2)perform the recon-all pipeline with the non-flipped volumes and flip only the final surfaces for statistical purposes?
Thank you for any suggestion
Kind regards
Paola
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