Thanks for the quick reply!
So if I understand correctly, the power of say the controls vs. diabetes (indeed it is type 2 diabetes) comparison is constrained by the sample size of the obese group?
2016-10-13 11:02 GMT-03:00 Bruce Fischl fischl@nmr.mgh.harvard.edu:
Hi Eelco
it isn't really a question of whether our implementation is senstitive to this. It's that in general your power will be constrained by the size of the smaller group (I assume this is Type 2 diabetes by the way).
cheers Bruce
On Thu, 13 Oct 2016, Eelco van Duinkerken wrote:
Hi all, I am using FS with data from 2 different studies that were acquired on
the
same MRI-machine with the same T1 and FLAIR sequences. Unfortunately, the group sizes are not very balanced, with 31 controls, 16 obese and 32 diabetes patients.
Is the GLM for thickness used in FS very sensitive to this unequal group size?
Thanks for the help,
Eelco
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