Hi Panos
I wouldn't trust the thickness from the ex vivo pipeline, and in any case those number are way to narrow a range. The normal cortex thickness ranges from about 1.5mm to 4 or 4.5mm. Getting reasonable thickness from ex vivo data is high on our to-do list
cheers Bruce
On Mon, 30 Jul 2018, Fotiadis, Panagiotis wrote:
Hi Bruce and Doug,
I have processed a few ex vivo brains with the help of the ex vivo freesurfer pipeline (outlined in https://surfer.nmr.mgh.harvard.edu/fswiki/ExvivoRecon), and have extracted their cortical thickness. So far the range of the cortical thicknesses have been approximately between 3.70-3.90 mm. Does that number sound reasonable for ex vivo brains? I am asking because the typical cortical thickness that I would expect to find on an in vivo brain would be between 2.05 - 2.35 mm.
Thanks in advance for any advice!
Best,
Panos
Panagiotis Fotiadis Senior Imaging Research Technologist J. P. Kistler Stroke Research Center, Department of Neurology Massachusetts General Hospital, Boston, MA T: (617) 643-3869