Hi Emma,
I might not be the only one who is unsure what you mean by a vertex-wise cortical surface area measure. Do you mean something like what is illustrated in figures 2 and 3 here:
http://www.pnas.org/content/107/29/13135.figures-only
… which is similar, but not identical to the local gyrification index?
If so, would you use this measure on surfaces before or after registration to a target atlas?
Donna
On Oct 10, 2014, at 4:19 PM, Emma Thompson voneconomos@gmail.com wrote:
Dear Freesurfers, I recently heard that there are several disadvantages to using a measure of cortical surface area in Freesurfer, specifically due to conducting a vertex-wise analysis. Can someone help me understand why a measure of surface area using this approach might be flawed? Thanks!