Hi EK
it's an empirical question. That is *very* anisotropic, so I suspect that there will be unavoidable biases in things like thickness maps which will be more accurate in regions in which the folds happen to place the cortex in the high resolution plane. That said, if the CNR is good enough it will probably generate reasonable surfaces.
cheers Bruce On Fri, 4 May 2012, EK Kim wrote:
Dear freesurfers, I wondered is it okay to analyze isotropic data which was converted to the anisotropic one. The original data has (0.390625, 0.390625, 1.5) mm size and (512, 512, 104) voxels. It obtained from 3T scanner. I know the Freesurfer recommend isotropic data (1,1,1)mm. Does it have any problem to use the data I just transformed? To do this, I rescaled the images and did bilinear interpolation to create an isotropic 8-bit version of images. Thanks for any help. EK