That is ok for thickness, but not for volume
On 2/9/2021 11:06 AM, Agurne Sampedro Calvete wrote:
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Dear Douglas,
I am doing both thickness and GM volume analyses. I am using a smoothing of 15. With a smoothing of 15, would a --cache of 2 be still too low? And would a --cache of 2 be too low for both thickness and volume analyses, or would it be adequate at least for volume analyses? Thank you very much.
Best regards,
Agurne
Neuropsychology of Severe Medical Conditions Research Team
Dpt of Methods and Experimental Psychology Faculty of Psychology and Education
University of Deusto
Avda. de las Universidades 24,
48007, Bilbao (Spain)
Phone: +34 944139000 (ext. 3015)
El mar, 9 feb 2021 a las 15:46, Douglas N. Greve (<dgreve@mgh.harvard.edu mailto:dgreve@mgh.harvard.edu>) escribió:
On 2/5/2021 9:54 AM, Agurne Sampedro Calvete wrote:External Email - Use Caution Dear Freesurfer experts, I am doing a longitudinal repeated measures ANOVA 2x2, with two groups (experimental vs control) and two time points (pre and post treatment). I have followed the group analysis tutorial ( *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/GroupAnalysis#GLMAnalysis.28mriglmfit.29 <https://secure-web.cisco.com/1pRD_UxgiIfPoYGdD-txQXbrB2PxuCy8sHKMjDgu-jv8mYA8xtQi6fT8t-cAQUuGG87avFRj2LEhHAIJlc1Awzxm1fIYMMnvHXmPOwiLnPZbiUN7Cyo5Mxqi2uNf8dw0M2_AMgq4opPKNVEeC65234qGSj1uEo4GtDxAL7c2MU4wI42FVRcau9LBBIWOQtTM_FMAGfwE7I5Td_KdKo1ppb_aUikrW8Sifb5gQuDAN-9u6FuzGdQ_I83Nns91USYKlhryBhDwhd2XauXyZHk9F9A/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsTutorial%2FGroupAnalysis%23GLMAnalysis.28mriglmfit.29> ), where it is suggested to do a Z Monte Carlo simulation with the following command: mri_glmfit-sim \ --glmdirlh.gender_age.glmdir \ --cache 4 neg \ --cwp 0.05\ --2spaces However, I have two questions regarding this issue: 1) I would like to know whether is it correct to use for example --cache 3 or 2 instead of 4. Is it recommended?Is this a thickness analysis? If so, 3 is probably ok, but 2 is too low; also depends on the smoothing level.2) Is it better to use, instead of the above Z Monte Carlo simulation command, a permutation with the following command?: mri_glmfit-sim \ --glmdir lh.gender_age.glmdir \ --perm 1000 4.0 abs \ --cwp 0.05\ --2spaces \ --bg 1The permutation will be more accurate, but at a threshold of 4, it probably won't matter much. But the good thing about permutation is that you can drop the threshold to 3 or 2 or even 1.3, and it will still do the right thing.Is it appropriate to use any of both? I do not know which is more recommended or whether both are adequate so I can simply choose, for example, the first one. Thank you very much in advance. Kind regards, Agurne Neuropsychology of Severe Medical Conditions Research Team Dpt of Methods and Experimental Psychology Faculty of Psychology and Education University of Deusto neurolab.deusto.es <http://secure-web.cisco.com/1UnrLWQpMMxdhKEG5HMrtIxWFxHsJTfrtXypEo9Dc-98NFX_4yPEsg2NqEqoQuReypFHAGq0aXxq1CsKiplAUMhJn3xTUmF95qk9IYP-L7373YTN8T8-RJR55wA1Gnu3iuM4MUGQwMR6SqTrWHWlhNVRjSS5BnRoz0lysXBO8ghrHRFlB-03jBzASp5QQha90nwuyk6z1jyP2lupIfhaAxZToPr7Ae2fnuSSJSl8bWpvgdWV6goduAv0Kk67utWKpRwjrBlEZcLB8IsAawzINIA/http%3A%2F%2Fneurolab.deusto.es%2F> Avda. de las Universidades 24, 48007, Bilbao (Spain) Phone: +34 944139000 (ext. 3015) _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://secure-web.cisco.com/1o5xCJkmepcQlQQeDkp6QMt3NbIsaoL0dbhkmgt22SqWKRSfgZBAxPHeA7O4N99tdHF4rXvEm-VlzRU1uVUUKRsgcluQ1RKR6_aKY1uaEu6S5VhNQlc6KiG0uqIYJ8ZNhSQeVE-xIiKG5A6FTI_UDmNqJR7WLdVljfcRknEVuO2sT4sqPreQnkeFRLCA9-Munx6OL1PXjdaEO_eccFqIIUMWsL7hnMedvn_RRRnsJS0TwTAwMMhu-9lu8rQVD6Y10JDqDHyxJ0fy45nVqcBhqCA/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer>_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://secure-web.cisco.com/1o5xCJkmepcQlQQeDkp6QMt3NbIsaoL0dbhkmgt22SqWKRSfgZBAxPHeA7O4N99tdHF4rXvEm-VlzRU1uVUUKRsgcluQ1RKR6_aKY1uaEu6S5VhNQlc6KiG0uqIYJ8ZNhSQeVE-xIiKG5A6FTI_UDmNqJR7WLdVljfcRknEVuO2sT4sqPreQnkeFRLCA9-Munx6OL1PXjdaEO_eccFqIIUMWsL7hnMedvn_RRRnsJS0TwTAwMMhu-9lu8rQVD6Y10JDqDHyxJ0fy45nVqcBhqCA/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer>
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