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Got it!
The 4 groups I'm testing are: CU cortisol low; CU cortisol high; CI cortisol low; CI cortisol high. So if I found a significant cluster for this contrast, can I interpret that the cortical thickness of this region of the cluster is affected by both the diagnosis and cortisol levels? In this case I made the correction of multiple comparisons with positive direction. That means that the worse the diagnosis and the cortisol levels (CI cortisol high) the more the cortical thickness of this region of the cluster will be affected, or to draw this conclusion would I need the results of the other contrasts as well?
Thanks so much for all the help!
Best, Laura Willers de Souza
Master Student in Biochemistry
Zimmer Lab - Federal University of Rio Grande do Sul
- Porto Alegre/RS - Brazil
________________________________ De: Douglas N. Greve dgreve@mgh.harvard.edu Enviado: quinta-feira, 17 de fevereiro de 2022 20:25 Para: Laura Willers de Souza laura.w.desouza@hotmail.com Assunto: Re: [Freesurfer] Question glm analysis g4v0
No, that was only for interactions between the covariates and the groups
On 2/17/2022 10:05 AM, Laura Willers de Souza wrote:
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Hello FreeSurfer Developers,
I am performing a GLM analysis to assess cortical thickness between 4 groups, without any covariates. I followed exactly what is on the wiki MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be https://secure-web.cisco.com/1U3sqGZa-FRgmgKfJEevEk2EOd_uv7vQJWJjf_LYazWAn4q...https://secure-web.cisco.com/1VuhMA49mKmIDKH_rGPy4c67MdbjL6bNv2i_WwNDwvMA5-MXr4tsqwQ6IStvSqNebMH5W36rEr0USbcPY6VSldSWInkjYUYATJN4-hScZf_-OvN7DjNFuD1LqLQPslKlEsRs2i5Frm5hCanY-mdYmoXDgRz99okbQHufSeXw7dl5Kao9r4PrXqZg1WBJq3pdh84vjS8osSMXbvqa3uhBkUhrQKMdQVsoDKPcfYvWBgQuvit_2zj-tuv-KuUpx8AwguemupjLL0D3erYK1Zx04S5eNVbsno35BFPDcDUyqYAvbdgwvH_RznbsqiWfBzdzKk5pv1hKHnRAHmRmAEopQBA/https%3A%2F%2Fsurfer.nmr.mgh.harvard.edu%2Ffswiki%2FFsgdf4G0V
In a previous analysis (MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be https://secure-web.cisco.com/1RhFqzblDwAITsckPrr706fDxu-1VP5A0p_2Z1L_dV6eBLI...https://secure-web.cisco.com/1qw-8Oc7vg0Tc3_ilXhnADw1_lWmUuUCQVr-MNNAiNRRR1O7MdJfPrEZTHnMCCdhrDYe2IGToziozmFZH9DmDjotHxZ13mSQ0meaYg54YZ3W49R5GmOOmv4pxtTQu6pCj6_X-TzVX_idBkKXYowz5SJjSSCz5SIX10hNl02tyfJRj7faXxmJCmpUARlF_WNVwe6Sh09yFRd_F6a9Q6mEUCZ0SjFdtnVii54is5AIDIJzLw_YXEx4Q_wEUnHtJoDca8nRl3HFIAZcmhGZIYKj_HK_8kUl0X_hKIh23Y9M1XOPEtCnVm3dt3tNuF7UX49wVzWEzktO7A9zzUhoAHRayaA/https%3A%2F%2Fwww.mail-archive.com%2Ffreesurfer%40nmr.mgh.harvard.edu%2Fmsg71673.html), Dr Douglas had told me that before any analysis I should test whether the interaction is significant or not.
I would like to know if this also applies to this case, the interaction being tested by contrast number 7 of the wiki.
Thanks in advance!
Best, Laura Willers de Souza
Master Student in Biochemistry
Zimmer Lab - Federal University of Rio Grande do Sul
- Porto Alegre/RS - Brazil
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