Hi Akemi,
I'm not sure I agree that area and thickness can't be independent. You could for example scale a spherical shell to be a smaller volume and area, but a constant thickness. In any case, you can get the #s you want from mris_anatomical stats:
mris_anatomical_stats $subject $hemi white mris_anatomical_stats $subject $hemi pial
should give you global values for the white and pial surfaces.
cheers, Bruce
On Wed, 28 Apr 2004, Akemi Tomoda wrote:
Dear list,
According to the results by running FS in our subjects, I have come to realize that the cortical surface area and gray-matter volume shrinks, while the cortical thickness tends to increase with a highly localized area of cortical thickening in the left hemisphere.
To my knowledge, these two variables (area, thickness) can not possibly be independent. So there must be a relationship because volume = area * thickness.
In order to test it statistically and look into the problem of interaction between thickness and area, I'd like to get the values of total out cortex surface area and total inner cortex surface area, separately.
I know FS use the white surface for surface area from the past ML (Pial Surface). I was wondering how I can get each value for out and inner cortex surface area.
Any suggestions are very welcome.
Akemi
Developmental Biopsychiatry Research Program McLean Hospital atomoda@mclean.harvard.edu
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