Actually, it is on by default (thanks to Emma for pointing it out). The smoothing helps to blur anatomical differences which reduces the chance that it will get stuck in a local minimum. It will usually only smooth the reference, and only if it is high res; this can help the reference look a little more like the moveable. In the end, I don't think it makes much of a difference except to make it a little more robust.
On 08/21/2017 03:52 PM, Douglas N Greve wrote:
I don't think that is turned on by default. There is smoothing of the NMI historgrams, but that is unrelated
On 08/21/2017 12:07 PM, John Anderson wrote:
Dear Dr Greve, Kindly, I wanted to know why "mri_coreg" apples smoothing during registration. e.g.
mri_coreg --s subject --mov template.nii.gz --reg template.reg.lta
Are there any effects on the accuracy of smoothing if I turn off this default feature (specifically in pet surfer pipeline).
mri_coreg --s subject --mov template.nii.gz --reg template.reg.lta --no-smooth
Thank you for any clarification John
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