If I understand you, you want to do a vertex-wise correlation between thickness and myelin. You can do this with a "per vertex regressor", --pvr input to mri_glmfit, something like
mri_glmfit --y thickness.mgh --pvr myelin.mgh --surf fsaverage lh --C contrats.mtx --o glmdir
with contrast.mtx being 0 1
This will set up a model thickness = offset + beta*myelin and then test whether beta=0
doug
On 11/18/2015 02:48 AM, Silas wrote:
I've mapped cortical thickness and the myelination data onto the fsaverage, and also used general linear modelling to investigate the one sample group mean of myelination data og cortical thickness (not very useful since the mean thickness or myelination should never be 0) data separately. I would like to map the correlation between cortical thickness and myelination onto the fsaverage. I've investigated this statistical correlation by a vertex wise correlation study in matlab, and it should be possible to map this onto the fsaverage. Though, I would like to perform this correlation study entirely in FreeSurfer - in this way I would easily be able to correlate for multiple comparisons using the standardized pipeline for FreeSurfer group analysis.
Best, Silas
From: freesurfer-bounces@nmr.mgh.harvard.edu freesurfer-bounces@nmr.mgh.harvard.edu on behalf of Douglas N Greve greve@nmr.mgh.harvard.edu Sent: Tuesday, November 17, 2015 7:10 PM To: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Multimodality analysis in FreeSurfer
I'm not sure what you mean. You say that you have mapped the thickness and myelin data into fsaverage space but then need to map the correlation into fsaverage. Isn't it already there?
On 11/17/2015 10:33 AM, Silas wrote:
Dear Freesurfer team,
I've scanned a group of subjects and gained structural and myelination data. Then, I've used mris_preproc to map the data onto the surface of fsaverage (and concatenating the data). I would like to investigate the correlation between cortical thickness and myelination by mapping this correlation onto the fsaverage (an one sample group mean analysis) - is this possible? Do you have an existing guide approaching this problem?
Thank you!
Best, Silas
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