Hi Freesurfer experts, I'm very sorry to bother you, but I am very confused with the following questions:
My experimental design includes two discrete factors: genotype with three levels (GG,GA,AA ); gender (F, M), and one covariate.
So I can get 6 classes: MGG, MGA,MAA, FGG,FGA,FAA.
1) I want to perform the difference between any of the genotype leves analysis with regressing out the effect of gender and one covariate, but I don't know the rules for setting the contrasts for the F-test. The contrast matrix I used is:
[1 -1 0 1 -1 0 0 0 0 0 0 0 ]/2
[1 0 -1 1 0 -1 0 0 0 0 0 0 ]/2
is it correct?
Any help will be very appreciated.
Best wishes,
Meng Li