Re: [Freesurfer] Track stats and covariates

Definitely age. You don't need to adjust for volume since these are not volume/area/length measures that you're comparing. You should also check for any group differences in motion before you proceed and make sure your groups are matched in terms of motion. If you do separate t-tests for each tract, you'll need to adjust for multiple comparisons (by the number of tracts).

On Tue, 20 Aug 2013, Alan Francis wrote:

Hi Anastasia: Just a quick question. When comparing FA, AD, RD etc between 2 groups, do we need to use covariates like Intra Cranial volume or AGE?

If the answer is no, should I do an ANOVA or will T tests be sufficient?

thank you,

Alan