External Email - Use Caution
Hi Jessica,
Samseg (https://secure-web.cisco.com/1JTcM_TfEicXTKVjm_oXuBpiFWbchbvUHpwl1Ti1WYPewF0...) should be able to do most of this. There are a few things it won't do, though: spine lesions, new lesions, and prefrontal cortex.
Koen
On Tuesday, June 30, 2026, Kasperek, Jessica < jessica.kasperek@endeavorhealth.org> wrote:
External Email - Use CautionHello,
One of my research studies, a retrospective Multiple Sclerosis (MS) study, is looking to conduct analyses on volumetric changes in brain MRI scans of MS patients during the course of their treatment. Specifically, it is looking for these items:
- Overall brain volume change
- Total lesion load
- Cervical spine lesion
- New MRI lesions
- Asymmetrical atrophy between left and right hemispheres
- Hippocampus
- Thalamus
- Basal ganglia
- Prefrontal cortex
- Cerebellum
- Cortical GM
Each patient has approx. 10 MRI scans or so. Is this a doable project for FreeSurfer? Any recommendations on how to approach this with the software? Any help is appreciated.
Thanks, Jessica
*Jessica Kasperek* *Research Coordinator* Neurology Department - Clinical Research Unit 1 Endeavor Health 2650 Ridge Avenue https://secure-web.cisco.com/1NuAdRCF6Zg0ftNoA1Q3cZ1Pr1miy2539z0NI4QY3Un8P6zBTAAlXFwDYlLpSvItpgqGIMtFQ-hdFwSX2hpp306wJPL52BGRZ8Ow9ccL5E-59yYH8Ro43_kkVh7xQp0lKP8WR_P1fOMTGsIZEHM20NbCDTlsGMsje-Tm_y_q9rn6XF-vopIIQ0suSycZ1SkPiGXUNjcsdiZgHLNhgoW5F4kYHI7f_ZfGxlcUQCxxDVqCYRN1wLRKER0wqRCWefWL8uzEmowaDst6iRRJTFbDUX0xtf23MTMHS90d0wvi_ozI2epg7aE0_wlCEBX3WTgymCmsj4O3DVqP2_2PmM1o4Hw/https%3A%2F%2Fwww.google.com%2Fmaps%2Fsearch%2F2650%2BRidge%2BAvenue%3Fentry%3Dgmail%26source%3Dg, Burch Building Room 310, Evanston, IL 60201 (p) 847-570-1864 (e) jessica.kasperek@endeavorhealth.org
******************* PLEASE NOTE ******************* This message and any documents accompanying this transmission may contain information that is privileged, confidential, and/or exempt from disclosure under applicable law and is intended solely for the addressee(s) named above. If you are not the intended addressee/recipient, you are hereby notified that any use of, disclosure, copying, distribution, or reliance on the contents of this message is strictly prohibited and may result in legal action against you. Please reply to the sender advising of the error in transmission and immediately delete/destroy the message and any accompanying documents. Thank you.
