It is probably reasonable to correct for either TIV or total HTh volume. Each of these tests a different hypothesis, so just know what hypothesis you are testing.
On 1/12/2022 10:32 PM, Xiaotong Zhang wrote:
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In the statistical analysis of the volume of the hypothalamus_seg, since the skull size of each person is different, it is necessary to exclude the influence of head size, that is, to regress the total intracranial volume, such as e TIV or sb TIV. I have a question: because the hypothalamus is the smaller subcutaneous nucleus, which indicator is more suitable for the analysis of the hypothalamus subregion? In addition, if the total volume of the hypothalamus as regression, is feasible? **
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Sincerely, Zhang
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