Hi all, I'm using Freesurfer to calculate cortical atrophy in patients with multiple sclerosis. These patients usually have also cortical lesions that I can see with DIR sequences. My question is: can I piece together the 2 sequences to see cortical lesions with FS? for FS we use a 3D fast-field echo (FFE) sequence: 120 contiguous axial slices with the off-centre positioned on zero, TR = 25 msec, TE = 4.6 msec, flip angle = 30°, slice thickness = 1.2 mm, matrix size = 256x256. DIR sequence: repetition time (TR) = 15631 msec, echo time (TE) = 25 msec, inversion time (TI) = 3400 msec, delay = 325 msec, echo train length (ETL) = 17, 50 contiguous axial slices with a thickness = 3 mm, a matrix size = 130 x 256, and a field of view (FOV) = 250 x 200 mm.
Thanks,
Irene Mattisi
Multiple Sclerosis Centre
Padua, Italy