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Dear all FS users, I wanted to know the way of accounting for gender in a simple regression analysis of cortical thickness against 2 continuous variables. Th example of contrast matrix given in the downloaded tutorial data for cortical thickness with age without accounting for gender is, 0 0 0.5 0.5 . However if we want to factor in gender how do we do it? Is it 0.5 0.5 0.5 0.5? or something else? Answers regarding same will be very much appreciated. Thanks, Dr. Rakshathi Basavaraju (MD Psychiatry) Postdoctoral Research Scientist Taub Institute Columbia University Irving Medical Centre 622 West, 168th Street, New York - 10032 E-Mail: rb3419@cumc.columbia.edumailto:rb3419@cumc.columbia.edu http://www.wellcomedbt.org/fellowsprofile/dr-rakshathi-basavaraju-288