Hi Jack, the problem isn't just the different folding, it's the contrast from the unmeylinated brain. We can't currently process brains from kids younger than about a year (or whenever adult T1 contrast is by and large established).
sorry, Bruce
On Wed, 2 Dec 2009, Schneider, Jacques wrote:
Hello to the freesurfer group,
I would like to analyze neonatal cortices with freesurfer. I ran a test data with a 10 yo child which came through wihtout problem. But a neonatal data set failed the recon at the level of talairach transformation. I suspect that the adult template is inconsistent with the neonatal immature folding and makes the transformation impossible. Now, Kazemi et al in NeuroImage 2007 published a neonatal template, and gave me the files on a research basis. My question is: how to replace the talairach coordinates in freesurfer with these neonatal data to make it work for this population ? I suspect the answer is not easy. But we are willing to give it a try, or perhaps are you already working on it ?
Cheers Jack
Dr. J.F. Schneider Head of Pediatric Radiology University Children's Hospital UKBB CH-4005 Basel Switzerland Phone +41 61 685 6282 Fax +41 61 685 6015 e-mail: jacques.schneider@ukbb.ch
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