[Freesurfer] GLM in groups with unequal size

Eelco van Duinkerken

13 Oct 2016 13 Oct '16

9:56 a.m.

Hi all,

I am using FS with data from 2 different studies that were acquired on the same MRI-machine with the same T1 and FLAIR sequences. Unfortunately, the group sizes are not very balanced, with 31 controls, 16 obese and 32 diabetes patients.

Is the GLM for thickness used in FS very sensitive to this unequal group size?

Thanks for the help,

Eelco

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