not sure what you are testing, but if you are, eg, looking at the difference between two groups regressing out ICV, then it can make a huge difference
On 08/29/2016 12:36 PM, Corinna Bauer wrote:
Hello all,
I am wondering why results would change completely for between group volume analysis when using demeaned/mean-centered ICV compared to using ICV as a covariate in mri_glmfit? See the figures below.
Does demeaning the covariate inherently change the results comapred to the raw covariate values?
Thanks
Corinna
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