At least by my reading of the Duvernoy Human Hippocampus atlas, the most anterior and posterior extents of the hippocmapus (perhaps just a slice at the tips in most scans) are almost entirely composed of the CA1 subfield. Thoughts?
Joshua - Joshua Lee Graduate Student Center for Mind and Brain & Department of Psychology University of California, Davis
On Thu, Nov 17, 2011 at 6:46 AM, Alan Francis alandarkenergy@gmail.comwrote:
Thanks Koen.
On Thu, Nov 17, 2011 at 6:14 AM, Koen Van Leemput < koen@nmr.mgh.harvard.edu> wrote:
The answer is close to what Shashwath suggested, except that the "Hippocampus" segmentation is really computed at the same time as all the other subfields. For unfortunate reasons, the tail of the hippocampus that is not further subdivided in our manual training segmentations was called "Hippocampus" for lack of other good names - it really should have been "Part of the Hippocampus Tail that We Didn't Subdivide Manually".
If you want to compute the total volume of the hippocampus, you'll need to add the volume of this part, though..
Hope this helps,
Koen
On Wed, Nov 16, 2011 at 2:10 PM, Alan Francis alandarkenergy@gmail.com wrote:
Thanks Shashwath.
On Wed, Nov 16, 2011 at 2:04 PM, Shashwath shashwath123@gmail.com
wrote:
Alan- I believe the label "hippocampus" here refers to the remaining
hippo
segment after the algorithm has completed labelling of all subfields.
In
essence this would not be a measure that conveys very meaningful info.
Sent from my iPhone
On Nov 16, 2011, at 1:01 PM, Alan Francis alandarkenergy@gmail.com wrote:
Hi Koen and FreeSurfers:
I have a 3T dataset that has undergone processing using 5.1. I have
also
run the Hippo sub fields command. Here are my results:
[root@NeuroImage-Gamma mri]# kvlQuantifyPosteriorProbabilityImages $FREESURFER_HOME/data/GEMS/compressionLookupTable.txt
posterior_right_*
posterior_Right-Hippocampus.mgz
volumeInVoxels: right_CA1: 2473.34 right_CA2-3: 7530.08 right_CA4-DG: 4160.99 right_fimbria: 520.14 right_hippocampal_fissure: 376.772 right_presubiculum: 2780.65 right_subiculum: 4230.04 Right-Hippocampus: 2277.69
My question is : Since these are "subfields" of the Hippocampus,
should
not the sum of all subregions be equal the volume of the Right
Hippocampus?
Thanks so much!
Alan Francis
Beth Israel Deaconess Medical Center, BOSTON
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