Hi Durai - Tracula is not for exploratory tractography, i.e., to answer questions like "what is this region connected to"? It uses prior anatomical information on known pathways to reconstruct those specific pathways. The anatomical information comes from the FreeSurfer anatomical segmentation of the same subject, and it's not just a seed region, but rather the probability of the pathway to go through each label in the anatomical segmentation at each point along the pathway's trajectory.
Hope this helps, a.y
On Sat, 29 Mar 2014, Durai Arasan wrote:
Hi Freesurfer experts, So I have seen studies where tracula was used to examine one of the 18 major tracts.
However can tracula perform seed based probabilistic tractography? i.e. can I seed ANY region and specify targets etc?
I guess I am asking if it can do LOCAL tractography of any kind?
Thank you!