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I have a group of stroke patients. Most of them have a left-sided stroke, the others right-sided. I would like to swap the affected right hemisphere with the unaffected left hemisphere in the patients with a right-sided stroke. I have done that successfully following the instructions with xhemi, but is there a way to achieve that for a regular group analysis (e. g. using fsaverage as the target and not to fsaverage_sym).
On Tue, Nov 5, 2019 at 9:24 PM Greve, Douglas N.,Ph.D. < DGREVE@mgh.harvard.edu> wrote:
what do you mean "flip" them?
On 11/5/2019 6:10 AM, Jose Graterol wrote:
External Email - Use CautionI believe I found my problem. I was trying to run the analysis with xhemi. Therefore it asked for 34 inputs (17subjects * 2 hemispheres). I was doing it that way because I flipped the hemispheres of the right affected stroke subjects. That was done with fscalc mul -1.
Now I have another question, would it still be possible to flip the hemispheres with fscalc while doing a normal group analysis? Or is there another way to flip them? I want to flip the hemispheres to have all the affected just in one side (e. g. the left hemisphere).
Thanks in advance.
On Thu, Oct 31, 2019 at 7:10 PM Greve, Douglas N.,Ph.D. < DGREVE@mgh.harvard.edu> wrote:
There are not any restrictions, just do the same as you would for a non-paired analysis. In any event, you are creating a linear model y = a +b1*x1 + b2*x2 ... where y is the input (paired diff) and x1, x2, etc, are your factors. You are the one who knows your data and what models would be appropriate
On 10/31/19 12:41 PM, Jose Graterol wrote:
External Email - Use CautionMy doubt is, if it is possible to use a FSGD file to add variables to a --paired-diff analysis. If it is, what would be the right way to format the FSGD file.
Thanks in advance.
On Wed, Oct 30, 2019 at 3:01 PM Greve, Douglas N.,Ph.D. <DGREVE@mgh.harvard.edu mailto:DGREVE@mgh.harvard.edu> wrote:
I don't understand. What per hemisphere variable? On 10/25/2019 3:15 AM, Jose Graterol wrote:External Email - Use Caution Thanks for your answer. A follow up question: How should I then specify the variable's values per hemisphere while making the FSGD file if I want to add covariates when running mri_glmfit? Thanks in advance. On Fri, Oct 25, 2019 at 12:18 AM Greve, Douglas N.,Ph.D. <DGREVE@mgh.harvard.edu <mailto:DGREVE@mgh.harvard.edu>> wrote: If you are trying to determine whether the hemispheres are different, then you need to do the subtraction between the hemis (ie, the --paired-diff). If you want to look at the hemispheres separately, then don't combine them in a single file On 10/21/19 4:58 AM, Jose Graterol wrote: > > External Email - Use Caution > > Thanks for your answer. > > I want to correlate TMS values in 17 stroke patients. Following the > instructions provided to Anders in this link >https://www.mail-archive.com/search?l=freesurfer@nmr.mgh.harvard.edu&q=s...
> I created the --y file that joins the affected hemispheres together > and the unaffected hemispheres together. I omitted the --paired-diff > flag. When I run mri_glmfit with --fsgd it asks for 34 inputs. I am > guessing those are for the 34 hemispheres of the patients in the order > mentioned in my first email. Would this be the right way to correlate > the variables? > > In short, I am trying to test if there is a difference in cortical > thickness, while adding covariates, between the affected and > unaffected hemispheres in stroke patients. > > Thanks in advance > > On Fri, Oct 18, 2019 at 3:57 PM Greve, Douglas N.,Ph.D. > <DGREVE@mgh.harvard.edu <mailto:DGREVE@mgh.harvard.edu> <mailto:DGREVE@mgh.harvard.edu <mailto:DGREVE@mgh.harvard.edu>>> wrote: > > What are you trying to test? Usually you don't have lh and rh in > the same glm > > On 10/17/19 7:09 AM, Jose Graterol wrote: >> >> External Email - Use Caution >> >> Dear Freesurfer Community, >> >> I have a question regarding the formatting of the FSGD file while >> doing an analysis with Xhemi. >> First the --y file was created as previously explained in another >> discussion >> (https://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg63965.html ).
>> That is, mris_preproc with --xhemi and no --fsgd flag. >> >> If I understood correctly, that would create a mgh file with the >> following order: sub01lh, sub01rh, sub02lh, sub02rh... >> Then the FSGD file while running mri_glmfit would be: >> GroupDescriptorFile 1 >> Title xxx >> Class sub >> Variables var1 >> Input sub01lh sub var1_lh_sub01 >> Input sub01rh sub var1_rh_sub01 >> Input sub02lh sub var1_lh_sub02 >> Input sub02rh sub var1_rh_sub02 >> >> Would this be correct? If so, what would be the best case for >> specifying a variable like age? Just repeating the value 2 times? >> >> As always, thanks in advance >> >> Kind Regards >> >> José >> >> >> _______________________________________________ >> Freesurfer mailing list >> Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu> <mailto:Freesurfer@nmr.mgh.harvard.edu <mailto:Freesurfer@nmr.mgh.harvard.edu>> >>https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
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