If you make a T1 map you can use that to look at differences in myelin content, but I don't know all of the ways to calculate T1 or if you could get that from only two flip angles. Two images with roughly the same contrast won't work for the ratio method. You need to have opposite contrast.
Also I'm not sure how a FLAIR would be better than a T2-SPACE.
Peace,
Matt.
From: Satrajit Ghosh satra@mit.edu Date: Tuesday, November 20, 2012 5:51 PM To: Matt Glasser matt@ma-tea.com Cc: "Watson, Christopher" Christopher.Watson@childrens.harvard.edu, "Winter, Warren" Warren.Winter@childrens.harvard.edu, "freesurfer@nmr.mgh.harvard.edu" freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Tool for incorporating T2-SPACE data in pial surface recons?
hi
matt: could you generate the myelin maps say from two flash scans at different flip angles?
bruce: if one had a choice between an mprage + t2 flair and 2 flash scans at 5/20 flip angles, what would be your recommendation?
cheers,
satra
On Tue, Nov 20, 2012 at 6:35 PM, Matt Glasser matt@ma-tea.com wrote:
If you get an MPRAGE and T2-SPACE you can make myelin maps too. FreeSurfer's final surface placement benefits a lot from high resolution images (less than 1mm) and you can still get good SNR with when you use 32-channel coils.
Peace,
Matt.
On 11/20/12 4:41 PM, "Bruce Fischl" fischl@nmr.mgh.harvard.edu wrote:
Yes, definitely. The t2-space flair is a big help
On Nov 20, 2012, at 5:40 PM, "Watson, Christopher" Christopher.Watson@childrens.harvard.edu wrote:
Hi Bruce, So would you recommend acquiring a T2 in addition to an (ME)MPRAGE/SPGR? i.e. is it worth squeezing another acquisition into a protocol?
Chris ________________________________________ From: freesurfer-bounces@nmr.mgh.harvard.edu [freesurfer-bounces@nmr.mgh.harvard.edu] on behalf of Bruce Fischl [fischl@nmr.mgh.harvard.edu] Sent: Tuesday, November 20, 2012 3:01 PM To: Winter, Warren Cc: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] Tool for incorporating T2-SPACE data in pial surface recons?
Hi Warren
yes, it will be part of the upcoming 5.2 release, hopefully in Dec. It will use either a FLAIR or T2 (ideally T2-SPACE for either one)
cheers Bruce On Tue, 20 Nov 2012, Winter, Warren wrote:
> Hi all, > > Back in January and October Bruce mentioned that he had under >development some scripts designed to utilize T2-SPACE images for better >pial surface reconstruction in the presence of dura -- I was just >wondering if any of that is ready for trial? > > Thanks! > > Warren > > -- > Warren Winter > Research Coordinator > Boston Children's Hospital > Sheridan Laboratory of Cognitive Neuroscience > Division of Developmental Medicine > 1 Autumn Street, AU 650 > Boston, MA 02215 > 857-218-5224 > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer > > >
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