One comment on power calculations. You cannot do the power calculations after you have completed the study. Any reviewer/referee asking you to compute the power should be politely informed that post-hoc power analyses are not valid and are biased (because you would be computing the power of the observed effect).
What you want to do is to compute the power of the experiment before you conduct the experiment. You want to be able to say that to compare an effect of X, we have have Y% power to detect the effect with N subjects.
G*Power is an excellent program to compute power - although it doesn't do it on the entire image.
Best Regards, Donald McLaren ================= D.G. McLaren, Ph.D. Research Fellow, Department of Neurology, Massachusetts General Hospital and Harvard Medical School Postdoctoral Research Fellow, GRECC, Bedford VA Website: http://www.martinos.org/~mclaren Office: (773) 406-2464 ===================== This e-mail contains CONFIDENTIAL INFORMATION which may contain PROTECTED HEALTHCARE INFORMATION and may also be LEGALLY PRIVILEGED and which is intended only for the use of the individual or entity named above. If the reader of the e-mail is not the intended recipient or the employee or agent responsible for delivering it to the intended recipient, you are hereby notified that you are in possession of confidential and privileged information. Any unauthorized use, disclosure, copying or the taking of any action in reliance on the contents of this information is strictly prohibited and may be unlawful. If you have received this e-mail unintentionally, please immediately notify the sender via telephone at (773) 406-2464 or email.
On Tue, Oct 29, 2013 at 10:25 AM, Douglas N Greve <greve@nmr.mgh.harvard.edu
wrote:
We don't have a way to do a power analysis directly from QDEC. I have some matlab code that does it for univariate analysis.
In the QDEC output folder, you will see a glm folder. In that there will be folders for each contrast. In the contrast folder, you will see an F.mgh file which will be the F-values. You can convert this to a t = sign(gamma.mgh)*sqrt(F)
doug
On 10/28/2013 07:27 AM, amirhossein manzouri wrote:
Hi Would you please let me know if it is possible to calculate the power
for a group comparison in cortical thickness? Also, a referee is requesting F-values and T map , are they generated by q-dec?
That would be great if I can get an answer in more detail since I have seen the post in FAQ, just need more information in detail regarding calculating the power ! -- Best regards, Amirhossein Manzouri
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
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