On 03/25/2013 10:52 AM, Gabriel Gonzalez Escamilla wrote:
Thanks a lot for your answer,
I'm sending you attached the diff of the two mris_preproc.
Those differences are just added features and won't change your results.
When I wrote CT, I was meaning cortical thickness, as normally this values are in surf/?h.thickness, But how do I know the Xhemi-registered thickness values of each subject for lh-rh, or area or any of those indices?
I'm not sure what you mean. When you run mris_preproc, you specify whether you want thickness, etc. doug
Regards, Gabriel
El 25/03/13, *Douglas N Greve * greve@nmr.mgh.harvard.edu escribió:
On 03/22/2013 06:45 AM, Gabriel Gonzalez Escamilla wrote:
Dear Doug,
I've seen that you restore the files to download, for the Xhemi registration. While I'm checking for the statistical process, I've seen that the one I have is: Date: 2012/12/06 16:06:52, Revision: 1.59.2.4, and the one that is on your ftp server is Date: 2012/12/06 16:06:17, Revision: 1.66, So mine is a lower version but recent hour, and the actual is newer version but seems that was created before the one I have. My question is, Which one should I keep?
Can you send me a diff of the two files?
If I change the mris_precproc version. Shall I re-run this step before statistical analyses, to create a new
lh.lh-rh.thickness.sm00.mgh?
On the other hand I have some doubts about the statistical procedure. It's supposed that if I apply the Xhemi registration, as result the left and right hemispheres are equals to each other on every
subject, so:
A) Where can I get the CT values after the Xhemi registration to FSaverage_sym for the left and right hemispheres?
what are CT values?
B) Given that I have two groups, Patients and Control, with two levels each, i.e male-female (Gp1male Gp1female Gp2male Gp2female Gp1maleVar1 Gp1femaleVar1 Grp2maleVar1 Grp2femaleVar1), and that I can set the contrasts and fsgd files as with a normal CT analisis, but only on my lh.lh-rh.thickness.smXX.mgh, wich is suppose to contain the left-right differences across subjects, right?
Wich would be the right interpretation? of:
The interpretation does not really change because it is a xhemi analysis
- 5 .5 -.5 -.5 0 0 0 0
Is the L-R difference between Grp1 and Grp2 different than 0 (regressing out Var1 and gender)
- 5 -.5 .5 -.5 0 0 0 0
Is the L-R difference between Males and Females different than 0 (regressing out Var1 and Group)
- 0 0 0 0 .5 .5 -.5 -.5
Does the slope of the L-R difference with Var1 differ between Grp1 and Grp2(regressing out gender)
- 0 0 0 0 5 -.5 .5 -.5
Does the slope of the L-R difference with Var1 differ between Male and Female(regressing out group)
Many thanks in advanced. Gabriel.
-- Douglas N. Greve, Ph.D. MGH-NMR Center greve@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422
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PhD. student Gabriel González-Escamilla Laboratory of Functional Neuroscience Department of Physiology, Anatomy, and Cell Biology University Pablo de Olavide Ctra. de Utrera, Km.1 41013 - Seville
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Email: ggonesc@upo.es http://www.upo.es/neuroaging/es/