it really depends on what the differences are. The best thing to do would be to scan some controls with both sequences and see what the differences are, although that won't rule out some disease-specific differences that you only see in the patients
On Thu, 28 Mar 2013, _andreia_@sapo.pt wrote:
Hello list,
I have a group of subjects (4 patients and 8 controls) in which one MPRAGE sequence was used and another group of subjects (2 patients and 2 controls) where a diffent MPRAGE was used. Both groups were acquired in the same scanner. For each subject I have two anatomical sequences and I'm working with the average dataset. My question is can I put both groups together for comparision?
I've thought about this and I can't really be sure... I was thinking that since for group 2 the number of acquisitions is balanced maybe the overall impact of different sequences won't be significative... Patients and subjects are age-matched in both groups.
Please, any advice will be greatly appreciated!
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