See https://surfer.nmr.mgh.harvard.edu/fswiki/PairedAnalysis
On 3/28/2022 3:18 AM, Agurne Sampedro Calvete wrote:
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Dear Douglas,
Do you mean calculate a type of change score (e.g. time2 minus time1) and then compare the differences between the two groups? How can I calculate the difference between the two time points? Thank you very much.
Best regards,
Agurne
El dom, 27 mar 2022 a las 23:07, Douglas N. Greve (dgreve@mgh.harvard.edu) escribió:
Probably the easiest thing to do since you have only two time points is to compute the difference between the two, then just do a simple group analysis where you include the covariates that you want. On 3/23/2022 10:00 AM, Agurne Sampedro Calvete wrote:External Email - Use Caution Dear FreeSurfer experts, I am doing a repeated measures ANOVA 2x2 (2 groups and 2 time points) and I would like to include in the analysis a covariate that is constant over the 2 times (e.g., baseline medication). I would like to see a "group x time x covariate" interaction. What should the design look like? I know that without covariate the design is as follows:GroupDescriptorFile 1 Class Subject1 Class Subject2 Variables Tp1vsTp2.Group1 Tp1vsTp2.Grroup2 Input Subject1_time1 Subject1 1 0 Input Subject1_time2 Subject1 -1 0 Input Subject2_time1 Subject2 0 1 Input Subject2_time2 Subject02 0 -1 Design matrix: 1 0 1 0 1 0 -1 0 0 1 0 1 0 1 0 -1 Contrasts (.mtx files): Tp1vsTp2.Group1 0 0 1 0 Tp1vsTp2.Group2 0 0 0 -1 Interaction (timexgroup) 0 0 1 -1However, I do not know how I could include the interaction with that covariate. Thank you very much in advance. Kind regards, Agurne _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://secure-web.cisco.com/1IuqXuXyJX5KD8JRY0t7329bqQKarO63jDbBFnaSqMtBNof0r4rJhamzR-1IFC7L5NF9QypcA0qEPLfHMAmIWZbY1k8L4vMUR2MX0VjfRsmyr4s5EJ_TT5ylipKF30Ro4H9Vgi-4F7Az2PUIeaX_C6lkIllxCGn4xH-FKcg8XGGTGhRNvVe2W_xHtet8hsbkegWqc2bynGCsRCmANRBiMOUlHLNhwYz77WVlgOic_d_uiVBtBGYTWppr8yOmjGxA0G0SVESVmxkIrOYLs1PQxdHRxXPjb6FrtimwGaF23cx8Go4F7YaCxeuMWNdB8NT-U/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer>_______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer <https://secure-web.cisco.com/1IuqXuXyJX5KD8JRY0t7329bqQKarO63jDbBFnaSqMtBNof0r4rJhamzR-1IFC7L5NF9QypcA0qEPLfHMAmIWZbY1k8L4vMUR2MX0VjfRsmyr4s5EJ_TT5ylipKF30Ro4H9Vgi-4F7Az2PUIeaX_C6lkIllxCGn4xH-FKcg8XGGTGhRNvVe2W_xHtet8hsbkegWqc2bynGCsRCmANRBiMOUlHLNhwYz77WVlgOic_d_uiVBtBGYTWppr8yOmjGxA0G0SVESVmxkIrOYLs1PQxdHRxXPjb6FrtimwGaF23cx8Go4F7YaCxeuMWNdB8NT-U/https%3A%2F%2Fmail.nmr.mgh.harvard.edu%2Fmailman%2Flistinfo%2Ffreesurfer> The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Mass General Brigham Compliance HelpLine at *MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://www.massgeneralbrigham.org/complianceline <https://secure-web.cisco.com/1x9B7YpCjD7VW1WOl4gdYgjWJaMAl6ZcCMJGhmN5gUtZ0YXG8Enkx51L_R3G0cJ693F_fG5lCRkt4sxeDiV13uqWwSBBh_dyzortnZiOS9drMMD_P-Au8qnLxyoMxq9TJmuajNMhlryO_xv-wNYC3iu1BLBD_kEsGxWrGA6-N6mF7A1nSHgnXIJgR2v-cmbpxUGY4MuhbsMa5U7WRmtPxHAdsunuA3KeCPkQmFjsE_jrbOB8wtLJtpozQAH_7EkqvXtPEwEQEBzflVC67XgqyMHWtSJPj3uY5ZyoKkIqjzXAhaXAKRtC7hi6nJ5Jq2vbw/https%3A%2F%2Fwww.massgeneralbrigham.org%2Fcomplianceline> <*MailScanner has detected a possible fraud attempt from "secure-web.cisco.com" claiming to be* https://www.massgeneralbrigham.org/complianceline <https://secure-web.cisco.com/1x9B7YpCjD7VW1WOl4gdYgjWJaMAl6ZcCMJGhmN5gUtZ0YXG8Enkx51L_R3G0cJ693F_fG5lCRkt4sxeDiV13uqWwSBBh_dyzortnZiOS9drMMD_P-Au8qnLxyoMxq9TJmuajNMhlryO_xv-wNYC3iu1BLBD_kEsGxWrGA6-N6mF7A1nSHgnXIJgR2v-cmbpxUGY4MuhbsMa5U7WRmtPxHAdsunuA3KeCPkQmFjsE_jrbOB8wtLJtpozQAH_7EkqvXtPEwEQEBzflVC67XgqyMHWtSJPj3uY5ZyoKkIqjzXAhaXAKRtC7hi6nJ5Jq2vbw/https%3A%2F%2Fwww.massgeneralbrigham.org%2Fcomplianceline>> . Please note that this e-mail is not secure (encrypted). If you do not wish to continue communication over unencrypted e-mail, please notify the sender of this message immediately. Continuing to send or respond to e-mail after receiving this message means you understand and accept this risk and wish to continue to communicate over unencrypted e-mail.
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