no, they should be aligned after applying the talairach.xfm, although the alignment is never perfect since it's only a 12 dof xform. How much bigger? If it's just a bit then you're probably ok.
cheers, Bruce On Wed, 10 Jan 2007, tulu wrote:
Dear Freesurfer experts,
I use fs 3.0.4 stable version on FC4. In recon-all stage 1, I check tkregister2 for my subject's MRI. I found the MNI305 template is large than normalized T1. Is it right ?
Thanks replay
KL Chen